This essay examines the doctrine of divine omnipresence. I begin by presenting three desiderata for an adequate account of omnipresence. Four accounts are analyzed in light of these desiderata, two in the tradition and two in contemporary philosophical theology. I argue that none succeed in providing an adequate account of divine omnipresence. As an alternative, I offer a paradoxical account of omnipresence, arguing that one can be rational in affirming that what appears to be a doctrine afflicted by apparent contradiction (...) is in fact merely a paradox. I explain what makes affirmations of paradoxical doctrines rational, why omnipresence should be understood as a paradox, and discuss a similar account of omnipresence in the writings of Pseudo-Dionysius the Areopagite. (shrink)

This paper explores the relationship between early modern English Puritanism and Reformed orthodoxy through a fresh examination of three ministers who have been described as Puritans: John Owen, Richard Baxter, and John Goodwin. By assessing their attitudes toward the Bible and specifically the doctrine of justification, this paper uncovers an evolving consensus of orthodox thought in the period. Their attitudes and approaches to doctrine and church tradition led to diverse interpretations and directions in the codification of their religion. Their theological (...) interpretations reflect an inherent pattern of diversity within English Puritanism, especially in its attitudes towards the formation of orthodoxy. The relation of Reformed orthodoxy to Puritanism, then, is more complex than older modes of scholarship have allowed. For the Puritan mainstream, Reformed orthodoxy served as a theological compass and thermostat that tested ideas and was to govern both the direction and temperament of Reformed doctrine. For those outside the pale, such orthodoxy and their alleged disloyalty to the Bible and Reformed church tradition was vehemently contested. (shrink)

Sex steroids, through their receptors, have potent effects on the signal pathways involved in osteogenic or myogenic differentiation. However, a considerable segment of those signal pathways has a prominent role in epithelial neoplastic transformation. The capability to intervene locally has focused on specific ligands for the receptors. Nevertheless, many signals are mapped to interactions of steroid receptor motifs with heterologous regulatory proteins. Some of those proteins interact with the glucocorticoid receptor and other factors essential to cell fate. Interactions of steroid (...) receptor domain motifs with heterologous proteins affect specific target pathways; consequently, manipulation of specified protein modules complexed with steroid receptors may be a next major step for enhancing molecular targeted therapeutics. In the future, intervention at specific sections of receptor primary sequence may prove therapeutically more efficient in targeting pathways of choice than ligand selectivity can be. (shrink)

2 Enoch 58–59 provides an esoteric and somewhat eccentric delineation of attitudes toward the mistreatment of animals within some sect of Egyptian Judaism, in all probability. Three attitudes, having to do with the mistreatment of animals in failing to feed them properly, the wrongful binding of animals for sacrifice, and possible secret sexual exploitation of animals, are delineated along with warnings regarding the effects of such treatment on the human soul at the great judgment. This linking of how humans treat (...) animals with how humans will be judged in “the great age” is unique in the literature of this period and demonstrates a deep concern for animal welfare that has been largely dormant in many facets of religion until more recent times. (shrink)

Interdisciplinarity is a notoriously difficult concept to define, and even harder to achieve in practice. All too often social approaches reduce science to an object of study, or conversely physical science approaches are invoked as a source of 'higher' truth. Drawing upon our experiences as ESRC-NERC PhD students within geography, we outline a paratactical approach that links disciplines by adjacency rather than hierarchy. Toppling the disciplinary hierarchy creates the potential for non-reductionistic dialogue between science and social science, but it also (...) raises a series of practical difficulties. These are considered around the themes of polyvocality, breadth over depth and (im)permanence. We suggest that while this kind of approach is increasingly encouraged by research funding bodies, it is less easily sustained within the everyday mechanics of the academic world. (C) 2006 Elsevier Ltd. All rights reserved. (shrink)

The λ model suggests that detailed kinematics arise from changes in control variables and need not be explicitly planned. However, we have shown that when moving a grasped object, grip force is precisely modulated in phase with acceleration-dependent inertial load. This suggests that the motor system can predict detailed kinematics. This prediction may be based on a forward model of the dynamics of the loaded limb.

Many upper limb amputees experience an incessant, post-amputation “phantom limb pain” and report that their missing limbs feel paralyzed in an uncomfortable posture. One hypothesis is that efferent commands no longer generate expected afferent signals, such as proprioceptive feedback from changes in limb configuration, and that the mismatch of motor commands and visual feedback is interpreted as pain. Non-invasive therapeutic techniques for treating phantom limb pain, such as mirror visual feedback (MVF), rely on visualizations of postural changes. Advances in neural (...) interfaces for artificial sensory feedback now make it possible to combine MVF with a high-tech “rubber hand” illusion, in which subjects develop a sense of embodiment with a fake hand when subjected to congruent visual and somatosensory feedback. We discuss clinical benefits that could arise from the confluence of known concepts such as MVF and the rubber hand illusion, and new technologies such as neural interfaces for sensory feedback and highly sensorized robot hand testbeds, such as the “BairClaw” presented here. Our multi-articulating, anthropomorphic robot testbed can be used to study proprioceptive and tactile sensory stimuli during physical finger-object interactions. Conceived for artificial grasp, manipulation, and haptic exploration, the BairClaw could also be used for future studies on the neurorehabilitation of somatosensory disorders due to upper limb impairment or loss. A remote actuation system enables the modular control of tendon-driven hands. The artificial proprioception system enables direct measurement of joint angles and tendon tensions while temperature, vibration, and skin deformation are provided by a multimodal tactile sensor. The provision of multimodal sensory feedback that is spatiotemporally consistent with commanded actions could lead to benefits such as reduced phantom limb pain, and increased prosthesis use due to improved functionality and reduced cognitive burden. (shrink)

In orthodox quantum mechanics, it has virtually become the custom to identify properties of a physical system with operationally testable propositions about the system. The causes and consequences of this practice are explored mathematically in this paper. Among other things, it is found that such an identification imposes severe constraints on the admissible states of the physical system.